Aline Pfefferle

This study identifies Ksp37 as a rapidly secreted NK cell protein that binds FGF2, suggesting a role in modulating extracellular environment and tumor-related processes.

This study shows that NKG2A expression in iPSC-derived NK cells drives functional specialization, enhancing cytotoxicity and IFN-γ production independent of HLA-E interactions.

The paper creates a single-cell reference map of NK cells and identifies tumor-associated states predictive of patient outcomes in melanoma and osteosarcoma.