Molecular BiologyNature CommunicationsPeer-reviewed
Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding
Mattia Conte, Ehsan Irani, Andrea M. Chiariello…·Mario Nicodemi
The paper compares loop-extrusion and polymer phase-separation models against chromatin data, finding they can co-exist in shaping single-cell chromatin architecture.