Dong Xing

scDIAGRAM detects chromatin compartments in single-cell Hi-C data without imputation or reference features, showing accuracy in simulated and real datasets.

This study identifies RAP80 as a target of HSV-1 ubiquitination enzymes ICP0 and UL36USP, showing how HSV-1 modulates host proteins at different infection stages to promote its survival.

The paper identifies resting NK cells that promote colon cancer liver metastasis by enhancing tumor-derived sSCF through cell-to-cell interactions.

The paper generates transcriptome and 3D genome atlases of developing mouse brain cells, revealing structure-type-based cell identity and experience-independent developmental changes.

The paper introduces GeACT, a genomic database for human mid-gestation fetus cells, linking gene expression to chromatin states and identifying key transcription factors.