ImmunologyNature CommunicationsPeer-reviewed
Rapid activation of IL-2 receptor signaling by CD301b+DC-derived IL-2 dictates the outcome of helper T cell differentiation
Naoya Tatsumi, Jihad El-Fenej, Alejandro Davila‐Pagan, Yosuke Kumamoto
The paper identifies CD301b+ DC-derived IL-2 as a key driver of Th2 differentiation by activating IL-2 receptor signaling in CD4 T cells, while inhibiting T follicular helper fate.
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