BiochemistryJACS AuPeer-reviewed
Molecular basis for short-chain thioester hydrolysis by acyl hydrolase domains in trans-acyltransferase polyketide synthases
Christopher D. Fage, Munro Passmore, Ben P. Tatman…·Matthew Jenner
The paper solves the structure of an acyl hydrolase (AH) domain and investigates its mechanism for hydrolyzing short-chain thioesters on acyl carrier protein (ACP) domains in trans-AT PKSs.