Author

Daniel Faessler

Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany;ORCID 0000-0002-8295-5390Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Ines ThieleiD· 2 shared Johannes HerteliD· 2 shared Alesia WalkeriD· 1 shared Almut HeinkeniD· 1 shared Ameneh Mehrjerd· 1 shared Andre FrankeiD· 1 shared Anna KöttgeniD· 1 shared Bram NapiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersSystems Biology

Ines ThieleORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintNov 12, 2026

Proton pump inhibitor-associated microbiomes shape systemic host responses

Karlis Arturs Moors, Saskia Weber-Stiehl, Hannah Jebens…·Christoph Kaleta

This study shows that PPI-associated microbiome changes cause systemic metabolic and transcriptional responses, affecting metabolism and inflammation in multiple tissues.

DOI 10.64898/2026.11.10.765563

humanmetagenomics

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Genetic & Genomic MedicinemedRxivPreprintOct 17, 2023

Coupling of metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and resulting traits and diseases

Nora Scherer, Daniel Fässler, Oleg Borisov…·Anna Köttgen

The paper identifies gene-metabolite associations using exome sequencing and metabolomics, revealing graded effects of rare variants on traits and diseases.

2 citations

humanwhole-exome sequencing

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