Pei‐Chung Lee

This study investigates how HSV-1 interacts with the host Hippo kinase pathway, showing that viral proteins like ICP0 counteract host defenses by modulating MST1/2 cleavage and apoptosis during infection.

This study shows that MST1/2 cleavage in macrophages mediates programmed cell death in response to sterile stimuli and bacterial pathogens, with distinct pathways depending on inflammasome activation.

This study shows MST1/2 control inflammatory Hippo signaling in macrophages, affecting cytokine release and restricting bacterial infection.