Oriol Llorà-Batlle

The paper identifies DNA sequence cis determinants that drive heterochromatin nucleation and maintenance in Plasmodium falciparum using genetic screening and chromatin immunoprecipitation.

The paper introduces Targeted DamID to detect cell-type specific histone modifications in vivo across different model organisms.

The paper demonstrates that the 10x Genomics Gene Expression Flex protocol can profile mixed human and mouse cells in xenografts by using combined probe sets and a pipeline to remove cross-reactive signals.

The paper uses a CRISPRi screen in human fetal lung organoids to identify SOX9 as a key regulator of progenitor self-renewal, showing it primes cells to receive WNT and RTK signals.