Author

Jacob T. Rutherford

Texas A&M Health Science CenterORCID 0000-0002-8447-4101Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Chetna DurejaiD· 1 shared Dianqing SuniD· 1 shared Fahad Bin Aziz Pavel· 1 shared Isaac PrahiD· 1 shared Julian Gregston HurdleiD· 1 shared Kirk E. HeveneriD· 1 shared Krissada NorseedaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Chetna DurejaORCID

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1 paper

Recent·Most cited

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedJan 24, 2024

In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) Inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy

Chetna Dureja, Jacob T. Rutherford, Fahad Bin Aziz Pavel…·Julian Gregston Hurdle

This study evaluates the in vivo efficacy of phenylimidazole 296 against C. difficile by targeting CdFabK, showing it retains microbiome stability better than vancomycin and fidaxomicin.

5 citations

C. elegansmouse

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