Author

Bruce A. Lessey

Atrium Health Wake Forest BaptistORCID 0000-0002-8451-2817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Chandrakant TayadeiD· 3 shared Danielle J SisnettiD· 3 shared Katherine B ZutautasiD· 3 shared Alison McCallioniD· 2 shared Harshavardhan LingegowdaiD· 2 shared Olga BougieiD· 2 shared Dan Hoang Nguyet VoiD· 1 shared Donya HayatiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

Chandrakant TayadeORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 18, 2026

Endometriosis patient-derived small extracellular vesicles carry unique immune, proteomic and lipidomic signatures associated with mild and severe endometriosis

Jaelis P. Holmes, Katherine B Zutautas, Danielle J Sisnett…·Chandrakant Tayade

This study identifies unique immune, proteomic, and lipidomic signatures in endometriosis-derived small extracellular vesicles associated with disease severity.

DOI 10.64898/2026.08.13.744471

humanproteomics

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ImmunologyThe Journal of ImmunologyPeer-reviewedFeb 24, 2025

Thymic stromal lymphopoietin contributes to endometriotic lesion proliferation and disease-associated inflammation.

Stanimira Aleksieva, Harshavardhan Lingegowda, Danielle J Sisnett…·Chandrakant Tayade

This study shows TSLP is overexpressed in endometriotic lesions and promotes cell survival and Th2 inflammation, supporting lesion proliferation.

3 citations

humanmouse

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ImmunologyThe Journal of ImmunologyPeer-reviewedMar 11, 2024

The dysregulated IL-23/TH17 axis in endometriosis pathophysiology

Danielle J Sisnett, Katherine B Zutautas, Jessica Eden Miller…·Chandrakant Tayade

This study investigates the role of the IL-23/TH17 axis in endometriosis by analyzing patient samples, cell lines, and a mouse model, finding dysregulated gene expression and increased IL-23 protein levels associated with disease severity.

30 citationstop 1%

humanmouse

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