Systems genetics identifies ETS1 as a stress-dependent regulator of adipocyte insulin action and heme-iron homeostasis
Yi Lin Jiang, Kristen C. Cooke, Harry B. Cutler…·Søren Madsen
Author
Harry Perkins Institute of Medical ResearchORCID 0000-0002-8562-7325Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Yi Lin Jiang, Kristen C. Cooke, Harry B. Cutler…·Søren Madsen
Stewart W. C. Masson, Rebecca C. Simpson, Harry B. Cutler…·David Ernest James
This study identifies a genetic locus affecting insulin sensitivity in mice, showing that Defa26 modulates glucose homeostasis through microbiome interactions.
Yvonne X. Kong, Rajan Rehan, Cesar L. Moreno…·Freda H. Passam
This study identifies SEC61B as a regulator of calcium flux and platelet hyperreactivity in diabetes by linking ER stress to increased SEC61B expression and calcium leak.
Diji Kuriakose, Grant Morahan, Zhi‐Cheng Xiao
The paper identifies Psmd13 as a regulator of miR-29a during neurogenesis, showing its interaction with Dicer and role in miR-29a expression dynamics.
Stewart W. C. Masson, Søren Madsen, Kristen C. Cooke…·David Ernest James
The paper identifies small molecules that reverse insulin resistance in mouse skeletal muscle by integrating systems genetics and chemical screening.
Jack A. Galbraith, Julien M. D. Legrand, N. Muller…·Kiarash Khosrotehrani
This study shows that host genetics significantly influences murine skin microbiota composition during homeostasis and wound healing, with genetic background explaining most variation in microbiota and healing speed.
Jocelyn Sietsma Penington, Megan A. S. Penno, Katrina Ngui…·Peter Vuillermin
This study evaluates how fecal collection conditions and 16S rRNA sequencing protocols affect gut microbiome analysis across two centers, finding that center-specific differences outweigh collection method variations.