Devesha Hrishikesh Kulkarni

This study shows lung-derived C3 initiates neutrophil recruitment in pneumonia before systemic C3, highlighting local complement's role in mucosal immunity.

This study shows that locally produced complement factor B in the gut reduces colitis, highlighting its role in mucosal immunity.

This study identifies a genetic variant linked to impaired complement regulation that worsens chronic lung allograft dysfunction-free survival by promoting B cell activation and donor-specific antibodies.

This study shows that inhibiting goblet cell-associated antigen passages (GAPs) during enteric infection promotes mucosal humoral immunity by mobilizing plasma cells, but requires a second signal for full IgA secretion.