Author
Ethan Ford
The University of Western AustraliaORCID 0000-0002-8563-199XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2017-2020 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 29 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Molecular BiologybioRxiv
A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs
Christian Pflueger, Dennis Eng Kiat Tan, Tessa Swain…·Ryan Lister
This paper develops a modular dCas9-SunTag DNMT3A system to improve DNA methylation editing specificity and reduce off-target effects compared to direct fusion constructs.
188 citations - GenomicsbioRxivPreprint
Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation
Ethan Ford, Matthew Grimmer, Sabine Stolzenburg…·Ryan Lister
Forcing DNA methylation onto thousands of human promoters with a zinc finger-DNMT3A fusion often fails to repress them, and the mark is quickly erased at H3K4me3-marked promoters.
45 citations