Gustavo Fuertes

This paper introduces a non-canonical amino acid that enables chemical control and spectroscopic readout of photoreceptor dynamics, revealing complex photocycle processes in a blue-light receptor.

The paper explores random protein sequence space to identify physical phenotypes and shows that sequence-based models can predict experimentally observed properties.

This study investigates how light-induced changes in the flavin cofactor of EL222 affect its conformation and DNA binding, revealing two distinct lit states and their role in photoactivation.