Author

Filip Buchel

Charles UniversityORCID 0000-0002-9041-5546Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Klára HlouchováiD· 2 shared Aleš BendaiD· 1 shared Alun R. C. JonesiD· 1 shared Brennen HeamesiD· 1 shared Dalibor PánekiD· 1 shared Erich Bornberg‐BaueriD· 1 shared Gustavo FuertesiD· 1 shared Margaux AubeliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSynthetic Biology

Klára HlouchováORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintMay 5, 2026

Learning the structural diversity in random protein sequence space

Filip Buchel, Tereza Neuwirthová, Theodora Tureckiová…·Klára Hlouchová

The paper explores random protein sequence space to identify physical phenotypes and shows that sequence-based models can predict experimentally observed properties.

1 citation

proteomicsexperimental assay

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Evolutionary BiologyGenome Biology and EvolutionPeer-reviewedApr 1, 2024

High-throughput selection of human de novo-emerged sORFs with high folding potential

Margaux Aubel, Filip Buchel, Brennen Heames…·Klára Hlouchová

This study identifies human de novo proteins with high folding potential by screening for structural compactness and disorder using FRET and FACS.

15 citations

humanproteomics

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