MicrobiologybioRxivPreprint
ISKNV-pORF71 hijacks outer mitochondrial membrane-localized VDAC2 to the nucleus, enhancing apoptosis by disrupting mitochondrial membrane permeability
Hetong Zhang, Yuting Fu, Youyong Dong…·Chuanfu Dong
This study shows that ISKNV-pORF71 hijacks VDAC2 from mitochondria to the nucleus, disrupting mitochondrial membrane permeability and enhancing apoptosis during infection.
DOI 10.1101/2025.11.13.688210