Romain Huguet

The paper introduces real-time library search (RTLS) to improve cross-link identification in XL-MS by leveraging intensity ratios of diagnostic peaks, enhancing identification depth in complex samples.

This paper uses cross-linking mass spectrometry to characterize Hsp70 interactions in budding yeast, revealing self-association, multi-point client interactions, and novel PTMs critical for client function.

This paper introduces an ultrasensitive single-cell proteomics workflow that identifies over 1000 protein groups per mammalian cell using advanced mass spectrometry techniques.