Linhao Ruan

This study shows ATF4 protects against doxorubicin-induced cardiomyopathy by enhancing H2S-mediated antioxidation through upregulation of CSE.

The paper compares TMEM106B pathology in murine models of neurodegenerative diseases to human postmortem tissue, identifying differences and convergent links to TDP-43 and Tau pathology.

This study shows inflammation-associated fibroblasts disrupt colon epithelial barrier integrity and genome stability via PGE2-EP4 signaling, and EP4 inhibitors can reverse these effects.

This paper uses cross-linking mass spectrometry to characterize Hsp70 interactions in budding yeast, revealing self-association, multi-point client interactions, and novel PTMs critical for client function.