Author

Serena Scala

IRCCS Ospedale San RaffaeleORCID 0000-0002-8579-3809Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alessandro AiutiiD· 1 shared Alex MurisoniD· 1 shared Alicia G. Aguilar-NavarroiD· 1 shared Anastasia ContiiD· 1 shared Clelia Di SerioiD· 1 shared Danilo PelliniD· 1 shared Edoardo CarsanaiD· 1 shared Elena Lo FurnoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Alessandro AiutiORCID

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2 papers

Recent·Most cited

Cell BiologyThe Journal of Experimental MedicinePeer-reviewedDec 5, 2025

Molecular and phenotypic blueprint of the hematopoietic compartment reveals proliferation stress as a driver of age-associated human stem cell dysfunctions

Emanuele Lettera, Luca Basso Ricci, Edoardo Carsana…·Raffaella Di Micco

The paper analyzes HSPC aging across the lifespan, finding age-related epigenetic dysregulation and impaired response to proliferative stress, using xenotransplantation models.

11 citationstop 3%

humanbulk RNA-seq

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BioinformaticsThe Annals of Applied StatisticsPeer-reviewedSep 1, 2023

TRACKING HEMATOPOIETIC STEM CELL EVOLUTION IN A WISKOTT-ALDRICH CLINICAL TRIAL

Danilo Pellin, Luca Biasco, Serena Scala…·Ernst C. Wit

This paper develops a statistical model to infer hematopoietic stem cell dynamics in a gene therapy trial for Wiskott-Aldrich Syndrome and finds evidence for a myeloid-based developmental pathway.

3 citations

humanbulk RNA-seq

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