NeuroscienceCommunications BiologyPeer-reviewed
Inhibiting glucocorticoid receptors enhances adult spinal cord neural stem cell activity and improves outcomes in spinal cord injury
DOI 10.1038/s42003-026-09901-7
Author
Fudan UniversityORCID 0000-0002-8609-8947Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Di Wan, Tongchuang Lu, Chenyang Li, Changlong Hu
This study shows glucocorticoids rapidly reduce Kv2.1 and CaV1.2 surface expression in hippocampal neurons, decreasing Ca2+ spikes through endocytosis of Kv2.1 clusters and reduced PKA activity.
Chengfang Pan, Ying Liu, Liangya Wang…·Changlong Hu
This study shows PGE2 inhibits glucose-stimulated insulin secretion in β-cells via the EP2/4-Kv2.2 pathway by modulating Kv2.2 channels through PKA.