Excess folic acid exposure increases uracil misincorporation into DNA in a tissue-specific manner in a mouse model of reduced methionine synthase expression
Katarina E. Heyden, Olga V Malysheva, Amanda J MacFarlane…·Martha S. Field
This study shows high folic acid intake increases uracil in DNA and γH2AX foci in colon tissue but not liver in mice with reduced methionine synthase expression.