Author
University of California, DavisORCID 0000-0002-8627-7208Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Diego López Mateos, Kush Narang, Vladimir M. Yarov-Yarovoy
This study uses AlphaFold2 to model multiple conformations of voltage-gated sodium channels and their interactions with protein partners, revealing structural diversity and conformational changes.
Megan M. Chinn, Diego López Mateos, Mary Ann Riley, Justin B. Siegel
This study designs new BACE-1 inhibitors using computational modeling, showing improved docking scores compared to Verubecestat for Alzheimer's disease treatment.
Nancy Daoud, Diego López Mateos, Mary Ann Riley, Justin B. Siegel
The paper computationally designs two novel μ-opioid receptor agonists with improved docking scores and ADMET properties compared to Hydrocodone.
Daniela Quiroz, Diego López Mateos, Kehan Zhao…·J. Grey Monroe
The paper shows H3K4me1 recruits DNA repair proteins to reduce mutations in functionally constrained regions of plant genomes.