Author

Di Yu

Johns Hopkins UniversityORCID 0000-0002-8636-0351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Hai‐Quan MaoiD· 2 shared Jinghan LiniD· 2 shared Jingyao MaiD· 2 shared Kailei D. GoodieriD· 2 shared Leonardo ChengiD· 2 shared Xiaoya LuiD· 2 shared Yining ZhuiD· 2 shared Bobby Y.X. NiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Hai‐Quan MaoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 2, 2025

Buffer Valency Engineering Enables High-concentration and Shelf-stable DNA Transfection Particles for Viral Vector Production

Jinghan Lin, Yizong Hu, Turash Haque Pial…·Hai‐Quan Mao

This paper develops a method to create high-concentration, shelf-stable DNA transfection particles for AAV production, achieving tenfold higher pDNA concentration and reduced dosing volume.

DOI 10.1101/2025.07.02.662322

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringbioRxivPreprintJan 27, 2025

mRNA lipid nanoparticle-incorporated nanofiber-hydrogel composite generates a local immunostimulatory niche for cancer immunotherapy

Yining Zhu, Zhi‐Cheng Yao, S.-H. Li…·Hai‐Quan Mao

The paper develops a nanofiber-hydrogel composite incorporating mRNA lipid nanoparticles to create a local immunostimulatory niche for cancer immunotherapy, showing enhanced immune responses with a single dose.

2 citations

experimental assaycancer & tumor microenvironment

𝕏 PostBluesky

BiophysicsAdvanced Functional MaterialsPeer-reviewedMar 13, 2024

Nanotopography boosts cellular uptake by inducing macropinocytosis

Morteza Aramesh, Di Yu, Magnus Essand, Cecilia Persson

This study shows that nanoporous surfaces enhance cellular uptake of genetic material and other molecules by inducing macropinocytosis, with optimal pore size of 400 nm.

7 citations

proteomicsmultiome

𝕏 PostBluesky