Paul S. Brookes

The paper identifies creatine kinase as a mediator of methylglyoxal's effect on mitochondrial permeability transition through proteomics analysis.

This study shows that deleting transglutaminase 2 improves metabolic support from astrocytes and reduces pathology after repetitive mild traumatic brain injury.

This study examines if charging for corrections in the Journal of Cancer disincentivizes pre-publication handling of problematic image data, finding a modest impact after policy change.

This study shows that loss of LATS1/2 in endothelial cells promotes a senescence-associated stemness (SAS) state, leading to atherothrombotic plaque formation through metabolic and mitochondrial dysregulation.

This study identifies the taurine-taurine transporter axis as a critical regulator of myeloid leukemia using temporal single-cell RNA-sequencing and functional experiments.

This study shows FZD2 inhibits YAP and prevents adult murine cardiomyocytes from reentering the cell cycle, and its deletion improves heart function and reduces scarring after myocardial infarction.

The paper investigates ROS generation during reperfusion, finding that Cx-I RET contributes less than previously thought, with other sources contributing significantly.

This study shows that neonatal hyperoxia inhibits atrial cardiomyocyte proliferation by suppressing fatty acid synthesis genes, leading to diastolic heart failure.