Cell BiologybioRxivPreprint
Lysosomal cystine efflux opposes mTORC1 reactivation through the TCA cycle
Patrick Jouandin, Zvonimir Marelja, Andrey A. Parkhitko…·Norbert Perrimon
The paper shows lysosomal cystine efflux limits TORC1 reactivation during fasting by restricting amino acid availability through TCA cycle intermediates.
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