Balaji Veeraraghavan

This study analyzes plasmid dynamics in CRKp clones to show lineage-specific resistance-virulence convergence through distinct plasmid configurations.

The paper develops and validates a genomics-informed multiplex PCR assay to specifically detect typhoidal Salmonella serovars, achieving high specificity and sensitivity.

This paper integrates host demographic and H. pylori genomic features to predict gastric cancer outcomes using machine learning, finding that age and genomic features improve prediction beyond traditional clinical data.

This study analyzes the genome of Klebsiella variicola from diverse sources to identify genetic adaptations linked to human infection.

The paper analyzes S. Paratyphi A isolates to show genome degradation and gene flux drive lineage evolution, with implications for public health surveillance.

The paper identifies ompC/F mutations as key factors in E. coli's XDR phenotype and lineage defining super clones, highlighting their role in carbapenemase gene acquisition and treatment challenges.

The paper analyzes SARS-CoV-2 genetic variants to identify stabilizing and destabilizing mutations and their impact on viral protein structure and function.

The paper reconstructs the evolutionary histories of antibiotic-resistant pneumococcal lineages PMEN3 and PMEN9, showing how interspecies recombination contributes to antibiotic resistance and serotype switching.

The paper identifies a carboxylic acid-containing compound as a potential inhibitor of NDM-1 through virtual screening and molecular dynamics simulations, showing higher binding affinity than Captopril.

This study analyzes ceftriaxone-resistant Salmonella Typhi isolates from India, finding that resistance arises from plasmid acquisition, with IncX3 and IncN plasmids contributing to sporadic resistance while IncY plasmids are associated with outbreaks in Pakistan.

The paper characterizes nine novel multidrug-resistant hypervirulent Klebsiella pneumoniae isolates in India, which harbor mosaic plasmids containing both antimicrobial resistance and virulence genes.

The paper analyzes genomic data from Shigella species in India, showing long-term persistence of S. flexneri and recent dominance of ciprofloxacin-resistant S. sonnei clones.

This study investigates the association between biofilm formation and carbapenem resistance in Klebsiella pneumoniae isolates, finding a positive correlation and significant impact on patient outcomes.

The paper reports the first whole-genome analysis of multidrug-resistant E. coli isolates from bloodstream infections in India, identifying key resistance and virulence gene profiles.

The paper reports complete genomes of two clinical B. pertussis ST2 strains from India, revealing genome degradation and virulence traits compared to vaccine reference strains.