Achim M. Hoerauf

This study identifies Wolbachia-infected sheath cells in filarial nematodes and shows that Fexinidazole and Corallopyronin A reduce Wolbachia clusters in these cells.

This study identifies eosinophils as a major source of IL-4 during filarial infections, showing their critical role in driving Th2 responses without affecting macrophage polarization or antibody production.

The paper estimates the number of adult helminth worms using genomic data from larvae to distinguish between treatment success and reinfection.

This paper establishes an in vitro culture system to maintain and develop Onchocerca volvulus larvae to adult stages, enabling study of mating, nodule formation, and drug screening.