Author

Young Hoon Koh

University of ChicagoORCID 0000-0002-8717-6089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:synaptic & neural circuits· 1

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Benoı̂t RouxiD· 1 shared Bernardo I. PintoiD· 1 shared Eduardo PerozoiD· 1 shared Francisco BezanillaiD· 1 shared Lydia BlachowicziD· 1 shared Ramon Mendoza UriarteiD· 1 shared Richa AgrawaliD· 1 shared Trayder ThomasiD· 1 shared

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Benoı̂t RouxORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintNov 13, 2025

Structure of the ILT Mutant Shaker K+ Channel and the Mechanism of Voltage Activation

Richa Agrawal, Ramon Mendoza Uriarte, Bernardo I. Pinto…·Benoı̂t Roux

The paper determines the cryo-EM structure of a Shaker K+ channel mutant and shows that voltage sensing domain activation induces a dynamic shift in the linker population equilibrium rather than directly pulling the gate open.

DOI 10.1101/2025.11.13.687653

cryo-EMdeep learning

𝕏 PostBluesky