Britt Christensen

This study identifies dysregulated epithelial cell death signaling in inflammatory bowel disease, showing it persists during remission despite therapy.

This study shows that partial reduction of BECLIN1 in intestinal epithelial cells leads to intestinal defects and increased susceptibility to inflammation, suggesting its importance in maintaining gut health.

The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.