Shene Chiou

This study shows that necroptosis in keratinocytes promotes differentiation and slows wound healing by preserving barrier integrity, suggesting it can be modulated to enhance tissue repair.

This study compares three RIPK3 kinase-dead variants to show that their scaffolding functions differ based on kinase domain conformation, not just kinase activity, and highlights implications for inhibitor development.

The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.