Author
University of MilanORCID 0000-0002-8756-0806Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Gorana Jendrisek, D. Mesa, Stefano Freddi…·Sara Sigismund
The paper identifies a RAC1-PLCγ2 axis that decodes EGFR ligand bias by linking receptor trafficking to metabolic programs supporting cell migration.
Amir Fardin, Andrea Francesco Benvenuto, Irene Schiano Lomoriello…·Sara Sigismund
This study identifies GL-Lect driven endocytosis as a driver of metastatic plasticity in breast cancer and shows pharmacologic inhibition can suppress invasive phenotypes.
D. Salvi Mesa, Elisa Barbieri, Andrea Raimondi…·Sara Sigismund
The paper shows that EGFR signaling via non-clathrin endocytosis requires a tripartite organelle platform linking Ca2+ oscillations to mitochondrial metabolism and ATP production for actin remodeling and collective motility.