Allele-resolved monosome and polysome sequencing identifies functional cis-acting variants affecting mRNA translation efficiency
Laura Alunno, Ilaria Massignani, Meriem Hadjer Hamadou…·Alberto Inga
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University of TrentoORCID 0000-0002-8767-1637Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
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Laura Alunno, Ilaria Massignani, Meriem Hadjer Hamadou…·Alberto Inga
Daniele Migliorati, Alessia Mattivi, Gian Mario Moretta…·Luca L. Fava
The paper investigates how centrosome architecture and m6A-dependent regulation influence p53 surveillance after whole-genome doubling, identifying key molecular mechanisms.
Meriem Hadjer Hamadou, Laura Alunno, Daniele Peroni…·Alberto Inga
Meriem Hadjer Hamadou, Laura Alunno, Tecla Venturelli…·Alberto Inga
The paper identifies a tranSNP in DDIT4 mRNA that affects translation efficiency and modulates p53-dependent responses in cancer cells.
Bartolomeo Bosco, Annalisa Rossi, Dario Rizzotto…·Alberto Inga
This paper shows DHX30 coordinates cytoplasmic and mitochondrial translation, affecting cancer cell survival and prognosis through a 15-gene signature.
Federico Zacchini, Giulia Venturi, Veronica De Sanctis…·Lorenzo Montanaro
The paper identifies dyskerin's role in regulating mRNA expression and nuclear hormone receptor dependence through snoRNA-retaining transcripts in breast cancer.
Fabio Lauria, Paola Bernabò, Toma Tebaldi…·Gabriella Viero
The paper shows SMN protein binds ribosomes and modulates translation of specific mRNAs in SMA, causing translational defects in motor neuron-related proteins.
Dario Rizzotto, Sara Zaccara, Annalisa Rossi…·Alberto Inga
This study identifies a translational control mechanism regulated by PCBP2 and DHX30 that determines the outcome of p53 activation by Nutlin, shifting the response from cell cycle arrest to apoptosis.