Daniele Peroni

This study identifies the YAP/NNMT axis as a driver of innate sensitivity to NAMPT inhibition in stem-like mesenchymal prostate cancer, suggesting NNMT as a biomarker for NAD+-targeting therapies.

This study investigates how TDP-43 dysregulation disrupts protein synthesis in ALS models by altering ribosome dynamics and mRNA homeostasis, revealing a conserved mechanism across in vitro and in vivo systems.

This study identifies small molecule inhibitors of hnRNPA2B1-RNA interactions and shows they alter EV-RNA composition and paracrine signaling.

The paper investigates how CD81-guided extracellular vesicles interact with breast cancer cells and deliver cargo, showing HER2 receptor influence on tropism and drug efficacy.

This study identifies NOC1 as a direct MYC target and shows its role in nucleolar function through protein interactions and structural changes.

The paper identifies 5HCEs in human 5UTRs, finds they are enriched in homeotic genes, and shows RBMX regulates these genes through post-transcriptional mechanisms.