Jovana Serbanovic‐Canic

Endothelial Twist1 drives partial and advanced endothelial-to-mesenchymal transition via PELP1 and AEBP1-COL4A1 signaling, increasing collagen and ACTA2+ cells to stabilize atherosclerotic plaques in male mice and human carotid arteries.

This study shows EPAS1 reduces atherosclerosis at disturbed flow sites by promoting endothelial fatty acid uptake and metabolism, which is suppressed in obesity through triglyceride-PHD3 pathway.

This study quantifies how absent blood flow affects vascular development in zebrafish cerebral and trunk vasculature, finding more severe effects in the brain.