David Lukacsovich

The paper identifies molecular and developmental diversity in CA1 border inhibitory neurons and shows their postnatal emergence of retrosplenial connectivity.

This study identifies DNA methylation changes in aging and Alzheimer's disease using brain and blood data, finding concordant CpG sites associated with AD progression.

The paper shows that Adgrl2 alternative splicing generates distinct isoforms in neurons and endothelial cells, with neuronal isoform expression in endothelial cells altering cerebrovascular properties and blood-brain barrier integrity.

This study identifies age-associated DNA methylation changes in blood and their overlap with Alzheimer's disease by analyzing two cohorts and finding shared genetic variants and CpGs associated with both aging and AD.

This study integrates DNA methylation profiles from tumors and organoids to identify CpGs predictive of chemotherapy response in rectal cancer, finding a methylation risk score significantly predicts progression-free survival.

The paper investigates the role of Neurexin-3 in sex-dependent GABAergic inhibition in the ventral subiculum, revealing sexually dimorphic synaptic functions at PV-RS and PV-BS synapses.

The paper identifies two distinct firing phenotypes of CCK+ interneurons in rat CA3 based on Kv4 auxiliary subunit isoforms, revealing how alternative splicing shapes cell-type identity.

The paper uses single-cell RNA-seq to analyze morphologically identified parvalbumin interneurons in mice, revealing transcriptomic homogeneity and an age-dependent onset of hemoglobin expression.