Daniel Álvarez

This paper evaluates AlphaFold3's performance across diverse structural biology tasks, finding uneven accuracy and strong dependence on training data.

This study uses molecular dynamics simulations to reveal the mechanism of lipid transport by BLTPs, showing membrane destabilization is critical for lipid desorption.

The paper uses cryo-EM to study the VPS13A-XKR1 complex, revealing how it facilitates lipid transfer between membranes and how this process is enhanced by membrane properties.

The paper identifies TMEM170 family proteins as lipid scramblases that physically interact with BLTP1/Csf1, revealing a new mechanism for lipid transport between organelles.

This study uses unbiased MD simulations to identify lipid binding pockets in LTPs, providing insights into lipid entry pathways for bridge-like LTPs.