Hannah C. Bennett

This study identifies age-related changes in cerebrovascular structure and function in the mouse brain, including reduced vascular length and increased tortuosity in specific regions.

The paper shows that impaired capillary-venous drainage in aging mice leads to hypoperfusion, gliosis, and demyelination in deep white matter regions.

The paper maps the spatial relationship between cerebrovasculature, pericytes, and neuronal cell types in mice to reveal how they support regional brain energy homeostasis.