Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewed
Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids
Yasuhiro M. Umemura, Nobuya Koike, Yoshiki Tsuchiya…·Kazuhiro Yagita
This study shows that CLOCK/BMAL1 disrupts the segmentation clock in mouse embryonic organoids by interfering with Hes7 oscillation and transcriptional regulation.
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