Ville P. Santala

This paper develops a 3D-printable, cytocompatible hydrogel from Acinetobacter baylyi ADP1 extracellular matrix, demonstrating its versatility for biofabrication.

This study shows that adaptive evolution can restore growth in a bacterium with a disrupted TCA cycle by reorganizing central metabolism and improving redox balance.

The paper introduces a dual chassis framework (DUET) to combine rational metabolic design with adaptive evolution, enabling robust microbial platform development.

This paper engineers Acinetobacter baylyi ADP1 to efficiently utilize pentose sugars and produce L-glutamate, achieving high growth rates and carbon yields.

This study engineers Acinetobacter baylyi ADP1 to produce naringenin by modifying its metabolism and introducing plant-derived enzymes, achieving 66 mg/L in fed-batch cultures.

This paper develops sRNA-based post-transcriptional repression cassettes to modulate BC crystallinity in K. xylinus, achieving gene expression reductions and structural changes in nanocellulose.

This study demonstrates a synergistic microbial system using anaerobic and aerobic bacteria to efficiently convert lignin-related compounds into valuable chemicals with minimal carbon loss.

This paper engineers a dynamic genetic circuit in Acinetobacter baylyi ADP1 to redirect carbon flow from biomass to wax ester production, improving yield and titer by over 3-fold.