Quinn E. Cunneely

The paper introduces a microfluidic T-Chip for one-step clinical-scale T-cell purification from blood products, achieving high purity, viability, and recovery of CD3+ T cells for CAR T-cell manufacturing.

In metastatic breast cancer on TROP2- or HER2-targeting antibody-drug conjugates, early CTC disappearance or steep decline tracked response, while CTC epitope levels neither predicted benefit nor vanished at resistance.

This paper introduces RAMP, a microfluidic method for precisely positioning cell streams in microchannels across a wide flow rate range, independent of particle size.

This study uses high-throughput microfluidic technology to enrich CTCs from large blood volumes, enabling detailed molecular and morphological analysis of tumor cells in metastatic cancer patients.