Tobias M. Hohl

This study shows that GM-CSF signaling in CCR2+ cells is essential for killing Aspergillus fumigatus and host survival during pulmonary infection.

This study shows that ampicillin treatment impairs neutrophil-mediated immunity to Aspergillus fumigatus in mice, increasing mortality and fungal burden.

The paper uses machine learning to identify valeric acid as a bacterial metabolite that inhibits Candida parapsilosis growth through intracellular acidification, reducing fungal colonization in mice.

The paper identifies an IFN-STAT1-CYBB axis that mediates protective crosstalk between plasmacytoid dendritic cells and neutrophils during Aspergillus fumigatus infection.

This study identifies GM-CSF produced by SPC+ epithelial cells as critical for neutrophil-mediated immunity against Aspergillus fumigatus, enhancing fungal killing and host survival.

This study shows perforin-2 is not essential for antifungal immunity against A. fumigatus and C. albicans in immune-competent mice, emphasizing the need for co-housed littermate controls.

This study shows that plasma membrane abundance regulates phagocytic capacity and post-phagocytic migration in myeloid cells, with G{beta}4 deficiency leading to increased phagocytosis and altered trafficking.

This study identifies that resistance to miltefosine in Candida parapsilosis arises from RTA3 gene amplification or flippase inactivation, altering plasma membrane lipid asymmetry.

The paper customizes a DADA2-based pipeline for fungal ITS1 amplicon datasets to improve species-level taxonomic annotation accuracy in clinical samples.

The paper identifies a new C. metapsilosis isolate resulting from a separate hybridization event, showing distinct genomic features compared to previously known isolates.