Roi Avraham

The paper uses image-based transposon screening to identify a flavin reductase that promotes Salmonella replication in macrophages by reducing oxidative and nitrosative stress.

The paper shows pneumococcal infection activates innate immune genes in only 1-4% of lung epithelial cells, contrasting with E. coli's 40% response, and identifies prostaglandin signaling as protective during invasive disease.

The paper uses single-cell transcriptomics to identify conserved and virulence-linked phenotypic states in bacteria.

This study develops a method to analyze microbiome DNA syntax using SIG-mers to distinguish healthy from diseased states across diverse populations.

This study shows that monocyte-derived microglia with a Dnmt3a mutation cause motor deficits in aging mice, resembling Parkinsonian disorders.

This study links hypoxia-related immune subsets in human and mouse models of Salmonella Typhi infection to disease outcomes.

This study identifies early and delayed STAT1-dependent responses in splenic macrophages that drive trained immunity, enhancing protection against Salmonella Typhimurium infection.