Author

Roland P. Piekorz

Düsseldorf University HospitalORCID 0000-0002-9105-2695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Mohammad Reza AhmadianiD· 2 shared Afshin Iram· 1 shared Alexander LangiD· 1 shared Björn StorkiD· 1 shared Constanze WiekiD· 1 shared Doreen Manuela FlossiD· 1 shared Helmut HanenbergiD· 1 shared Isabell Lehmkuhl· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Mohammad Reza AhmadianORCID

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2 papers

Recent·Most cited

BiochemistryFEBS Open BioPeer-reviewedNov 20, 2025

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel…·Roland P. Piekorz

This study shows SIRT4 promotes autophagy by modulating ULK1 phosphorylation, independent of HDAC6 and OPA1, and identifies its role in early autophagy initiation.

DOI 10.1002/2211-5463.70164

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintNov 23, 2023

Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling

Mehrnaz Mehrabipour, Radovan Dvorsky, Saeideh Nakhaei-Rad…·Roland P. Piekorz

This study identifies SIRT4 as a specific interactor of C-RAF kinase, showing it suppresses MAPK signaling by stabilizing the inactive form of C-RAF.

DOI 10.1101/2023.11.23.568463

humanproteomics

𝕏 PostBluesky