Author

Michelle Y. Chan

Gladstone InstitutesORCID 0000-0002-9105-9977Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Ashkan JavaherianiD· 2 shared Jeremy W. LinsleyiD· 2 shared Nicholas A. Castello· 2 shared Steven M. FinkbeineriD· 2 shared Anthony Q. VuiD· 1 shared Ashmita Baral· 1 shared David KokeliD· 1 shared Dominik HaddadiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Ashkan JavaherianORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedSep 6, 2021

Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

Jeremy W. Linsley, Kevan D. Shah, Nicholas A. Castello…·Steven M. Finkbeiner

This paper introduces GEDI, a fluorescent biosensor that detects early irreversible commitment to cell death in neurons, enabling real-time and high-throughput analysis of neurodegeneration.

36 citations

mousehuman

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NeuroscienceNeuronPeer-reviewedJul 1, 2019

Modulation of RNA-dependent interactions in stress granules prevents persistent TDP-43 accumulation in ALS/FTD

Mark Y. Fang, Sebastian Markmiller, Anthony Q. Vu…·Gene Wei-Ming Yeo

The paper introduces VariantKey, a reversible numerical encoding for genetic variants, and presents compounds that inhibit stress granule formation and TDP-43 accumulation in ALS/FTD models.

287 citationstop 1%

humanwhole-genome sequencing

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