Evolutionary BiologybioRxivPreprint
Environment-dependent epistasis shapes adaptation to fluctuating resources.
Ashlynn G Bruder, Nathan Fiedeldey, Sarah B. Worthan…·Megan G. Behringer
This study shows how fluctuating environments shape genetic interactions in E. coli by selecting for mutations in transport genes that exhibit environment-dependent epistasis and improve fitness across feast and famine conditions.
DOI 10.64898/2026.07.31.742109