Author

Kedric L. Milholland

Purdue University West LafayetteORCID 0000-0002-9154-6441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:drug response / drug discovery· 2 Research Focus:perturbation response prediction· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Mark C. HalliD· 3 shared Jaime Correa‐BordesiD· 2 shared Scott D. BriggsiD· 2 shared Smriti HodaiD· 2 shared Ahmed AbdelKhalekiD· 1 shared Andrew G. DeMarcoiD· 1 shared Angela N Koeberlein· 1 shared Antonio Esperilla-Muñoz· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Mark C. HallORCID

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3 papers

Recent·Most cited

Molecular BiologymSpherePeer-reviewedAug 21, 2026

Expansion and optimization of the auxin-inducible degron 2 (AID2) system in Candida pathogens

Emily L. Danzeisen, Michelle V. Lihon, Kedric L. Milholland…·Mark C. Hall

The paper expands and optimizes the AID2 system for use in Candida species, including clinical isolates and C. auris, enhancing its utility for protein function studies.

DOI 10.1128/msphere.00359-26

C. elegansexperimental assay

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Molecular BiologymSpherePeer-reviewedAug 18, 2023

Rapid, efficient auxin-inducible protein degradation in Candida pathogens

Kedric L. Milholland, Justin B. Gregor, Smriti Hoda…·Mark C. Hall

This paper demonstrates the efficient use of auxin-inducible degradation systems in Candida pathogens for rapid protein inactivation.

11 citations

yeastexperimental assay

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Molecular BiologybioRxivPreprintSep 29, 2022

Reduced Cdc14 phosphatase activity impairs septation, hyphal differentiation and pathogenesis and causes echinocandin hypersensitivity in Candida albicans

Kedric L. Milholland, Ahmed AbdelKhalek, Kortany Maree Baker…·Mark C. Hall

This paper shows that reducing Cdc14 phosphatase activity in Candida albicans impairs cell wall integrity, septation, hyphal differentiation, and virulence, making it a potential antifungal drug target.

2 citations

C. elegansmouse

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