Laia Reverte-Salisa

This study shows that activating perivascular thermogenic fat reduces aortic stenosis in mice and correlates with less severe AS in humans.

The paper develops a mathematical model of the canonical AhR pathway to identify which biochemical steps drive ligand-specific transcriptional responses using qPCR data from mouse macrophages.

This study investigates the cell type-specific roles of AhR and AhRR in diet-induced obesity and fibrosis, finding that AhRR deficiency protects from metabolic dysfunction and liver damage, while AhR deficiency worsens outcomes.