Brian F. Pfleger

This study identifies ACAD10 and ACAD11 as enzymes critical for metabolizing 4-hydroxy fatty acids in mammals, revealing their unique mechanisms and subcellular localization.

This study improves gene expression and transformation efficiency in Picosynechococcus sp. PCC 7002 by optimizing protocols and identifying a better integration site.

This paper develops a model-guided framework to design high-diversity synthetic human gut communities by optimizing culture conditions and leveraging ecological models.

EnZymClass predicts plant acyl-ACP thioesterase substrate specificity using ensemble learning, achieving high accuracy and outperforming existing methods.

This study uses machine learning to engineer acyl-ACP reductases for improved in vivo fatty alcohol production, achieving over twofold higher titers than natural enzymes.

The paper describes the design and construction of an affordable photobioreactor system capable of cultivating up to 12 independent 1 L cyanobacterial cultures at a cost lower than a single commercial unit.