Gérard Karsenty

This study shows that bone-derived hormone osteocalcin regulates locomotion by maintaining mitochondrial function in spinal motoneurons, and that this effect can be reversed in aged mice.

This study identifies a muscle-sympathetic nerve-intestine network that drives inflammation and atrophy in immobilized muscles, showing that intestinal inflammation contributes to muscle damage.

This study shows that removing GLUT1 in astrocytes improves brain and peripheral glucose metabolism without affecting cognition, due to increased insulin-stimulated ATP release.