Franck Oury

This study identifies PTH1R signaling in AgRP neurons as a mechanism controlling feeding behavior and nutrient partitioning through distinct kinase activation and lipophagic processes.

This study shows that bone-derived hormone osteocalcin regulates locomotion by maintaining mitochondrial function in spinal motoneurons, and that this effect can be reversed in aged mice.

This study identifies rare RYR3 variants causing recurrent rhabdomyolysis by impairing autophagy and mitochondrial function, highlighting RyR3's role in muscle stress adaptation.

This paper introduces a computational framework to identify genetic mouse models for rare obesity, revealing links between obesity and 16 other diseases.

This study shows maternal and embryonic osteocalcin work together to maintain homeostasis in offspring by affecting insulin secretion, glucose metabolism, and steroidogenesis.

This study examines Foxp2 expression patterns in a humanized mouse model and finds region-specific shifts in striatal expression levels associated with behavioral changes.